Opportunity Information: Apply for MP CPI 26 001

The National Lupus Outreach and Clinical Trial Education Program (Funding Opportunity Number: MP CPI 26 001) is a discretionary federal grant opportunity administered by the Office of the Assistant Secretary for Health. It funds health-focused projects (CFDA/Assistance Listing 93.137) designed to improve participation in lupus clinical trials among populations that have been historically underrepresented. The central aim is to support integrated, community-based models that help people move through the entire clinical trial participation pathway, not just initial outreach. That pathway explicitly includes raising awareness, generating and facilitating referrals, supporting screening and eligibility steps, improving enrollment, and strengthening retention so participants can stay engaged through study completion.

The program is looking for practical, community-centered approaches that connect clinical research infrastructure with trusted local touchpoints. In plain terms, the emphasis is on building or expanding coordinated models where community organizations, health systems, and research sites work together to reduce real-world barriers that prevent equitable participation in lupus trials. By calling for integrated models, the opportunity signals interest in solutions that do more than provide information; they should also create workable handoffs and support systems that translate awareness into actual trial entry and sustained participation. The focus on education and outreach suggests that applicants should plan to address common obstacles such as lack of knowledge about trials, limited access to specialty care or research sites, mistrust, logistical burdens, and drop-off during screening or follow-up.

Eligibility is broad and includes many types of public, private, nonprofit, academic, and tribal entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); and for-profit organizations other than small businesses. This wide eligibility range allows proposals from organizations that are already embedded in communities as well as those that operate research or clinical trial infrastructure, and it supports partnerships that combine community trust with clinical trial capability.

Financially, the grant has an award ceiling of $500,000 per award, and the agency expects to make approximately six awards. The opportunity was created on 2026-06-10, and the original application closing date is 2026-07-10. Overall, the funding is intended to help applicants design and implement community-based systems that measurably increase underrepresented groups participation in lupus clinical trials from first exposure to a trial opportunity through long-term retention, with the larger goal of making lupus research participation more equitable and the resulting evidence more representative of the people affected by the disease.

  • The Office of the Assistant Secretary for Health in the health sector is offering a public funding opportunity titled "National Lupus Outreach and Clinical Trial Education Program" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.137.
  • This funding opportunity was created on 2026-06-10.
  • Applicants must submit their applications by 2026-07-10. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • The number of recipients for this funding is limited to 6 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses.
Apply for MP CPI 26 001

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Frequently Asked Questions (FAQs)

What is the National Lupus Outreach and Clinical Trial Education Program?

It is a discretionary federal grant opportunity that supports health-focused projects designed to improve participation in lupus clinical trials, especially among populations that have been historically underrepresented.

What is the Funding Opportunity Number (FON) for this grant?

The Funding Opportunity Number is MP CPI 26 001.

Which federal office administers this grant?

The program is administered by the Office of the Assistant Secretary for Health.

What is the Assistance Listing (CFDA) number?

The Assistance Listing (CFDA) number is 93.137.

What is the main goal of this funding opportunity?

The main goal is to support integrated, community-based models that help people move through the entire lupus clinical trial participation pathway, from initial awareness through sustained retention to study completion.

What does the program mean by the "clinical trial participation pathway"?

The pathway explicitly includes raising awareness, generating and facilitating referrals, supporting screening and eligibility steps, improving enrollment, and strengthening retention so participants can remain engaged through study completion.

Does the program focus only on outreach and education?

No. While education and outreach are emphasized, the opportunity is specifically interested in solutions that go beyond information-sharing and create workable handoffs and support systems that translate awareness into actual trial entry and continued participation.

What types of project approaches does the program appear to prioritize?

The program emphasizes practical, community-centered approaches that connect clinical research infrastructure with trusted local touchpoints, including coordinated models where community organizations, health systems, and research sites work together.

Who is the intended focus population for improved trial participation?

The focus is on populations that have been historically underrepresented in lupus clinical trials.

What barriers is the program encouraging applicants to address?

Based on the opportunity description, applicants are expected to plan for common obstacles such as lack of knowledge about trials, limited access to specialty care or research sites, mistrust, logistical burdens, and participant drop-off during screening or follow-up.

What does "integrated, community-based model" mean in this context?

It refers to coordinated systems that link community trust and local access (for example, community organizations) with clinical and research capacity (for example, health systems and research sites) to support participants across awareness, referral, screening, enrollment, and retention.

Is this opportunity designed to support partnerships?

Yes. The broad eligibility and the emphasis on connecting community touchpoints with clinical research infrastructure indicate strong alignment with partnership-based models that combine community presence with trial capability.

Who is eligible to apply?

Eligibility includes a wide range of entities: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); and for-profit organizations other than small businesses.

Can nonprofit organizations apply if they do not have 501(c)(3) status?

Yes. Nonprofit organizations with or without 501(c)(3) status are listed as eligible (with the noted exclusion related to institutions of higher education within those nonprofit categories).

Are institutions of higher education eligible?

Yes. Both public/state-controlled institutions of higher education and private institutions of higher education are listed as eligible.

Are tribal entities eligible to apply?

Yes. Federally recognized Native American tribal governments and tribal organizations that are not federally recognized tribal governments are included in the eligibility list.

Are for-profit organizations eligible?

Yes, for-profit organizations other than small businesses are listed as eligible applicants.

What is the maximum award amount per grant?

The award ceiling is $500,000 per award.

How many awards does the agency expect to make?

The agency expects to make approximately six awards.

When was this funding opportunity created?

The opportunity was created on 2026-06-10.

What is the application closing date?

The original application closing date is 2026-07-10.

What outcomes is this funding intended to support?

The funding is intended to help applicants design and implement community-based systems that measurably increase participation of underrepresented groups in lupus clinical trials, from first exposure to a trial opportunity through long-term retention.

Why does the program emphasize retention through study completion?

The opportunity description highlights that improving equity in clinical trial participation includes not only enrolling participants but also strengthening retention so participants can stay engaged through the entire study.

What larger impact is the program aiming for?

The larger goal is to make lupus research participation more equitable and to ensure the resulting evidence is more representative of the people affected by lupus.

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