Opportunity Information: Apply for HRSA 21 076
This HRSA Special Projects of National Significance (SPNS) funding opportunity (HRSA 21 076) supports a single national Coordinating Center for Technical Assistance under a cooperative agreement, designed to improve health outcomes for people with HIV by finding, testing, and spreading innovative service approaches. The award is intended to run for up to four years and uses an implementation science framework to move beyond simply proposing promising ideas. The emphasis is on identifying practical intervention strategies, piloting them in real-world Ryan White HIV/AIDS Program (RWHAP) settings, supporting sites with hands-on technical assistance, and then packaging what works into tools other providers can replicate.
The initiative is organized around four focus areas that reflect both priority populations and a service delivery opportunity where stronger approaches could lead to better HIV outcomes. The first three focus areas target groups that often face layered barriers to consistent HIV care and viral suppression: people with substance use disorder, LGBTQ youth, and people who are or have been incarcerated. The fourth focus area centers on telehealth, recognizing that remote and technology-enabled care can potentially improve access, retention, and continuity of services when implemented well. Across these areas, the program is looking for interventions that can be implemented in RWHAP-funded environments and that are likely to improve outcomes such as engagement in care, retention, adherence, and viral suppression.
A core responsibility of the Coordinating Center (referred to as the 2iS CCTA) is to run a competitive process to solicit, select, issue, and manage subawards to implementation sites. The CCTA is expected to subaward up to 20 RWHAP recipients or subrecipients, roughly five sites per focus area, with each site piloting one intervention strategy aligned to one of the focus areas. Subawards can be up to 190,000 per year per site. Selection is based on demonstrated need and capacity, meaning sites must show they have both the reason to address a particular gap and the operational ability to put an intervention into practice.
Beyond making and monitoring subawards, the CCTA is the technical assistance backbone of the initiative. It is expected to provide structured, ongoing TA to help subawardees successfully adopt and deliver the interventions, troubleshoot implementation challenges, and effectively engage clients. This role is not limited to general guidance; it is intended to support real implementation, including helping sites integrate new workflows, strengthen staff competencies, and maintain fidelity while adapting appropriately to local context. The CCTA also has a major product-development role: it must create dissemination and replication materials that allow other HIV service organizations to adopt successful approaches quickly. These products might include implementation guides, training materials, workflows, protocols, toolkits, and other practical resources that translate lessons from the pilots into step-by-step instructions.
Evaluation is handled through a separate, companion cooperative agreement: the Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV - Evaluation Center (2iS EC, HRSA-21-068). The Evaluation Center is responsible for assessing uptake and implementation of the piloted interventions and examining associated client outcomes at the subawarded sites. The relationship between the CCTA and the Evaluation Center is intentionally collaborative: the CCTA supports and coordinates implementation and TA across sites, while the Evaluation Center measures what happened and what changed. Importantly, the evaluation findings are meant to drive dissemination decisions, meaning the evidence generated by the Evaluation Center will inform which replication tools the CCTA ultimately promotes and how broadly those tools should be shared.
Administratively, this is a discretionary HRSA opportunity in the health activity category (CFDA 93.928) offered by the Department of Health and Human Services through HRSA. It was posted December 18, 2020, with an original closing date of March 8, 2021, and HRSA anticipated making one award for the Coordinating Center. The notice also references an earlier SPNS effort (HRSA-17-044 and HRSA-17-049) as the prior initiative for which this opportunity served as a competing continuation, signaling that the program builds on an established SPNS model of piloting innovations, evaluating them, and accelerating replication across HIV care systems.Apply for HRSA 21 076
- The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV - Coordinating Center" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.928.
- This funding opportunity was created on Dec 18, 2020.
- Applicants must submit their applications by Mar 08, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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